Rithvik Marri1, Harini Rao2, Diana S Osorio1, Jonathan L Finlay1
1 Division of Pediatric Hematology/Oncology, Nationwide Children’s Hospital, The Ohio State University, USA
2 Children’s Hospital of New Jersey, Newark Beth Israel Medical Center, USA
Corresponding author: Diana S Osorio, Division of Pediatric Hematology/Oncology, Nationwide Children’s Hospital, The Ohio State University, Columbus, Ohio, USA
Received: December 11, 2018
Published: January 17, 2019
Background: Hearing impairment and tinnitus are forgotten features of Parinaud Syndrome originally discussed by Henri Parinaud in 1886.
Methods: A retrospective case series of 3 patients who presented with pineal region germinomas and hearing loss.
Results: A 15 years old male presented with morning headaches, blurred vision, bilateral papilledema, failure of upward gaze, bilateral tinnitus and decreased hearing acuity. Post-operatively, his tinnitus disappeared completely and his hearing normalized within one week. A 16 years old male presented with complete left-sided hearing impairment with cranial nerve III palsy, right eye ptosis and worsening right-sided hearing loss; he had minimal recovery of his hearing after therapy. A 46 years old with a recurrent germinoma presented with hydrocephalus, bilateral ophthalmoplegia and hearing loss; his hearing loss improved after surgical resection.
Conclusion: These case reports serve as a reminder that hearing loss can also be a component of Parinaud Syndrome.
Keywords: Hearing loss; Pineal region tumor; Germinoma; Germ cell tumor; Tinnitus; Parinaud Syndrome